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Products: Kinases: PAK1KD

PAK1KD (recombinant human PAK1 kinase domain)

Catalog #: Size: Concentration: Price:
K0104S 10 µg 1 mg/ml $360
K0104M 100 µg 1 mg/ml $1,320
K0104L 1 mg 1 mg/ml $5,640
K0104B Bulk 1 mg/ml Inquiry


To Order: Please email PO to order@accelagen.com or fax PO to 888-239-6490


PRODUCT DETAIL DATA SHEET
Description:
Human PAK1 kinase (UniProt: Q13153; NCBI: NM_002576) belongs to a family of p21-activated kinases. These serine/threonine kinases serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK1 kinase regulates cell motility and morphology.

PAK1KD is a recombinant wild type human PAK1 kinase domain (amino acids 248–545 of full-length human PAK1) expressed in E. coli and purified to near homogeneity. PAK1KD does not have the inhibitory switch domain and has high specific activity.

Molecular Mass and Phosphorylation:
The calculated mass is 33,646. PAK1KD is fully phosphorylated at T423 and partially phosphorylated at additional sites with measured mass of 33,728 (1P), 33,808 (2P), 33,889 (3P), and 33,968 (4P).

Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.

Applications:
Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization



Protein Purification | Baculovirus Expression | Mammalian Expression | E. coli Expression | Molecular Biology | Proteins

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