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Products: Kinases: PAK3KD

PAK3KD (recombinant human PAK3 kinase domain)

Catalog #: Size: Concentration: Price:
K0106S 10 µg 1 mg/ml $510
K0106M 100 µg 1 mg/ml $1,966
K0106L 1 mg 1 mg/ml $7,240
K0106B Bulk 1 mg/ml Inquiry

To Order: Please email PO to or fax PO to 888-239-6490

Human PAK3 kinase (UniProt: O75914; NCBI: NM_001128166) belongs to a family of p21-activated kinases. These serine/threonine kinases serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. Overexpression of PAK3 has been detected in certain types of cancer. Mutations of PAK3 have been associated with learning disability and X-linked mental retardation.

PAK3KD is a recombinant wild type human PAK3 kinase domain (amino acids 246-544 of full-length human PAK3) expressed in E. coli and purified to near homogeneity.

Molecular Mass and Phosphorylation:
The calculated mass is 33,758. PAK3KD is phosphorylated on T421 and partially phosphorylated at additional sites with mass measured at 33,835 (1P), 33,915 (2P), 33,995 (3P).

Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.

Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization

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