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Products: Kinases: PAK4KD

PAK4KD (recombinant human PAK4 kinase domain)

Catalog #: Size: Concentration: Price:
K0107S 10 µg 1 mg/ml $510
K0107M 100 µg 1 mg/ml $1,996
K0107L 1 mg 1 mg/ml $7,240
K0107B Bulk 1 mg/ml Inquiry

To Order: Please email PO to or fax PO to 888-239-6490

Human PAK4 kinase (UniProt: O96013; NCBI: NM_005884) belongs to a family of p21-activated kinases. These serine/threonine kinases are regulated by the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.

PAK4KD is a recombinant wild type human PAK4 kinase domain (amino acids 300–591 of full-length human PAK4) expressed in E. coli and purified to homogeneity with full activity.

Molecular Mass and Phosphorylation:
The calculated mass is 33,309. PAK4KD is fully phosphorylated at S474 with a measured mass of 33,389 (1P).

Stability and Storage:
Stable at -70oC for 12 months from date of receipt. Protein should be thawed on ice. Protein can be flash-frozen in liquid nitrogen and stored at -70oC.

Enzymatic studies, inhibitor screen, and selectivity profiling
High concentration available for crystallization

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